South Korea 
What is Poly-L-Lactic Acid?
When a suspension of poly-L-lactic acid (PLLA) microcrystals in saline solution is injected into the skin, it activates fibroblasts and stimulates the formation of collagen around the microscopic acid particles. After approximately two weeks, the liquid component is absorbed by the body, and the injected area is gradually replaced by the patient's own tissue, which forms a network around the PLLA particles. Over time, the acid naturally breaks down into carbon dioxide and water, leaving behind a dense collagen framework.
Injection of poly-L-lactic acid initiates a cascade of rejuvenation processes within the skin. Stimulated fibroblasts (skin cells) actively produce structural proteins such as collagen, elastin, and fibronectin, as well as components of the extracellular matrix including hyaluronic acid, sodium hyaluronate, and glycosaminoglycans. These processes help restore, regenerate, and rejuvenate the cellular and extracellular composition of the skin.
aesPLLa® Treatment Protocol
- 4 sessions spaced 3–4 weeks apart
- Results last up to 2 years after completing the full course